Emerging Molecular Approaches and Their Significance in the Diagnosis and Management of Hepatitis C Virus Infection

نویسندگان

  • Sumera Naz
  • Attya Bhatti
  • Mohammad Shoaib Khan
چکیده

Molecular biology based assays are invaluable tools for the diagnosis and management of chronic viral hepatitis. They can be used to test donor’s blood, to diagnose active infection, guide treatment decisions, assess the virological response to therapy and establish the prognosis. For hepatitis C infection, these include serological assays for anti-HCV antibody detection and molecular assays that detect and quantify HCV-RNA and determine the HCV genotype. This article reviews the current molecular biology based techniques and assays and their practical use in the management of hepatitis C virus infection.

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تاریخ انتشار 2008